Clinical basis

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Clinical basis

Clinical evidence: effect of sonic vibration

Short-term Effects of Sound Vibration Therapy on Motor Impairments in Parkinson’s Disease
LK King, QJ Almeida, H. Ahonen
NeuroRehabilitation 25 (2009) 297-306 as doi: 10.3233/NRE-2009-0528
ISO Press
Experiment method:
-For 40 people with Parkin’s disease.
-The treatment continues for 10 minutes.
-The music vibration is produced and controlled in 6 steps, programmed to deliver local sound waves.
-Measure progress and effectiveness of treatment methods using the Unified Parkinson’s Disease Rating Scale (UPDRS).

-Improved in areas such as stiffness, proprioceptive sensation, and gait of all muscle functions.
-In particular, the stiffness has been reduced, there has been a lack of streaks, the gait has improved significantly, and the speed has been increased.

Vibroacoustic Sound Therapy Improves Pain Management and More
C. Boyd-Brewer, R. McCaffrey
Holistic Nurs Pract 2004;18(3):111-118
May/June 2004

Three positive influences:
First, it affects pain and symptom relief as well as tension, fatigue, headache, tingling, and depression.
Second, at a frequency between 60-600 Hz, the Pacinian corpuscle (sensory nerve) promotes the pain suppression of pain.
Third, vibration also helps mechanisms that positively affect health and pain.

Low-Frequency Vibratory Sound Induces Neurite Outgrowth in PC12m3 Cells in which Nerve Growth Factor-Induced Neurite Outgrowth is Impaired
Y. Koike, S. Iwamoto, Y. Kimata, T. Nohno, F. Hiragami, K. Kawamura, K. Numata, H. Murai, K. Okisima, M. Iwata, Y. Kano
Tiss. Cult. Res. Commun. 23:81-90(2004)
2004 Japanese Tissue Culture Association

The purpose of this paper is to clarify how music therapy affects Alzheimer’s disease.
PC12 cells are useful as a model of undifferentiated cell models that affect the activation of the NERVE GROWTH FACTOR (NGF) that affects the expansion of nerve cells and nerve stumps.
MAPK’s activities play an important role in the growth of the nervous system of PC12 cells.

– Frequency of low sound waves (10-100 Hz) increased to neurite outgrowth.
– Sound wave frequencies (150-200 Hz) are also affected.
– The activation of MAPK (cell protein chain) plays an important role in PC12m3 cells.
– 40 Hz low sound frequency stimulates p38 MAPK activity and p38 MAPK activity stimulates the signal to PC12m3 cells.
Proof that it affects the growth of the connecting nerve bumps.

Effects of a Low-Frequency Sound Wave Therapy Program on Functional Capacity, Blood Circulation and
Bone Metabolism in Frail Old Men and Women
A. Zheng, R. Sakari, SM Cheng, A. Hietikko, P. Moilanen, J. Timonen, KM Fagerlund, M. Karkkainen, M. Alen, S. Cheng
Clin Rehabil OnlineFirst, published on Aug, 28, 2009 as doi: 10. 1177/0269215509337273

Experiment method:
-A total of 49 elderly people participated. Sit in a sonic therapy chair under a nurse’s guide for 6 months, 3 to 5 times a week, 30 minutes each.
-Blood pressure and temperature were measured by a nurse before and after 30 minutes of treatment.
-Controlled and implemented with low frequency sound waves within the range of 27-113Hz.

-Improvement of functional ability in movement
-Cholesterol reduction.
-Reduced difficulty in walking and movement after the experiment.
-Increased physical activity.
-Sonic therapy using low frequencies has the potential to increase movement/functional ability.

-2018 Orthopedic Academy of Open Medicines, published a paper on the effect of pain relief and inflammation in ligament surgery
-Mode 3 applied to EVOCELL product.

-2019 Journal of the French Society of Physical Therapy
-Comparison of the method using mode 3 sound source and 5 music with EVOCELL product
-Pain and inflammation relief has the same effect, but the stimulation of music has a lot of influence on psychological stability.